This study presents a comparative analysis of structuralist architecture and Iranian residential architecture, exploring their distinct characteristics and cultural significance. The investigation commences with an introduction to both architectural styles, highlighting their historical contexts and foundational principles. It then delves into key components such as spatial organization, material usage, structural logic, and environmental interactions. The research employs a descriptive-analytical approach within an interpretive paradigm. With an applied aim, the study utilizes inferential methods in its theoretical framework. Information is gathered through library and documentary research, drawing on sources such as books, articles, and scholarly investigations. Initially, content analysis is used, relying on theoretical foundations to examine concepts such as Iranian architecture, its elements and components, and the concept of Structuralist architecture with its specific approach. Subsequently, the relationships between these elements are discussed. Findings demonstrate that Structuralist architecture prioritizes flexibility and innovation, whereas Iranian architecture, characterized by central courtyards and traditional materials, emphasizes community and environmental responsiveness, as evidenced in historic houses. The research highlights the contrasting yet complementary nature of both styles, underscoring their valuable insights into sustainable design practices. The conclusion posits that integrating the robust cultural narratives of Iranian architecture with the modern, dynamic approaches of structuralism can enhance future architectural endeavors, fostering spaces that prioritize both heritage and innovation. This synthesis can lead to designs that are not only functionally efficient but also culturally rich and environmentally sustainable.